What is colchicine, what are its side effects? Is colchicine effective against corona virus? – Health News

Professor of Cardiology at Istanbul University Cerrahpaşa Medical Faculty Cardiology Institute. Dr. Nazmi Gültekin and Clinical Microbiology Specialist Assoc. Dr. Emine Küçükateş, known as Ibn-i Sina’s magic medicine, wild crocusderived from colchicine started a scientific study on it.

Colchicine is a herbal medicine derived from bitter crocus in our country. Two Turkish doctors, history Ibn-i SinaFirst used colchicine based on cardiac patients.

When successful results were obtained in patients, the study was first published in an international medical journal called JPMA (Journal of Pakistan Medical Association) in Pakistan in 2014. After the Corona virus epidemic, it was tested on intensive care patients in many countries around the world and successful results were obtained.


Colchicine is a medicine used to treat gout and Behçet’s disease. It is less preferred than NSAIDs or steroids in gout. Other uses for colchicine include prevention of pericarditis and familial Mediterranean fever. It is used in the treatment of various rheumatic diseases as well as being researched for cancer treatment.


Colchicine has a narrow therapeutic index and therefore overdose is a significant risk. Common side effects of colchicine are gastrointestinal upset, especially at high doses. Severe side effects can include low blood cells and rhabdomyolysis and can be fatal if the drug is overdosed. It is unclear whether colchicine is safe for use in pregnancy, but it appears to be safe to use during breastfeeding. Colchicine works by reducing inflammation through multiple mechanisms.


Stating that colchicine can be used as an anti-infection, anti-inflammatory against corona virus. Dr. Nazmi Gültekin said, “On top of that, this magic drug was used in intensive care and outpatients in Italy, Spain and Russia, where the highest number of Covid-19 cases and death rates were experienced in March and April last year. It reduces the cytokine storm in Covid-19 cases and stops it in most cases. When the defense system weakens, viruses become active. Meanwhile, some patients experience a cytokine storm. This mysterious drug reduces this storm. “

Prof. Dr. Gültekin said, “The success rate of corona virus patients in intensive care units is remarkable. A thesis topic was also made in our country and presented at international meetings. But it should not be forgotten that colchicine should definitely be applied by the physician. “


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